Paradoxical activation of eNOS by NADPH Oxidase 5
نویسندگان
چکیده
منابع مشابه
Paradoxical activation of endothelial nitric oxide synthase by NADPH oxidase.
OBJECTIVE Increased formation of reactive oxygen species (ROS) has been identified as a causative factor in endothelial dysfunction by reducing NO bioavailability and uncoupling endothelial nitric oxide synthase (eNOS). However, the specific contribution of ROS to endothelial function is not well understood. METHODS AND RESULTS A major source of intracellular ROS is the NADPH oxidase (Nox) fa...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2008
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.22.1_supplement.758.29